Directed by Alex Garland who is best known for the 2015 Oscar-nominated film Ex Machina, Annihilation is a visually dazzling and thought-provoking sci-fi movie notable for its rather strange and frightening story and a terrific performance from Oscar-winner Natalie Portman. Based on the acclaimed 2014 novel of the same name written by Jeff VanderMeer, the plot revolves around Portman’s character Lena who is a biologist and former American soldier that unexpectedly becomes involved in a highly classified mission to study and prevent the spread of a scientifically unexplained phenomenon known as The Shimmer located along the American coast in a rapidly expanding region known as Area X. After her husband Kane, played by Golden Globe nominee Oscar Isaac, mysteriously returns a year after going missing on an expedition into Area X, Lena is recruited to go on another mission to study The Shimmer and determine whether it is earthly or extraterrestrial. It is a particularly dangerous operation because no one besides her husband has ever returned after that many failed attempts. Led by the stone-faced psychologist named Dr. Ventress, played by Jennifer Jason Leigh, the all-female group of scientists is comprised of a paramedic named Anya, played by Gina Rodriguez, a physicist named Josie, played by Tessa Thompson, and a surveyor and geologist named Cass, played by Tuva Novotny. Immediately after venturing into Area X, Lena and the rest of the team notice that things are very abnormal, including the plants and animals exhibiting perplexing biological mutations. The filmmaker mystifies the audience through the realistic and often beautiful depictions of these strange creatures; towards the end, reality and the laws of nature become further blurred as emphasized by the ever increasing mind-blowing imagery witnessed by the characters. Not just purely science fiction, the film contains several suspenseful and often terrifying moments that could come from a horror flick, especially the scenes involving mutated animals and the psychoses experienced by the team members. Overall, I found it to be a riveting and creative work of science fiction that surprisingly delves deep into philosophical issues of humanity and our relationship to the environment, while also catering to fans of sci-fi and horror with its mesmerizing visual effects and creation of horrifying creatures.